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Two fully equipped research laboratories: one for drug pre-formulation, formulation and preparation (Galenic Laboratory) and one for drug analysis/characterization (Drug Analysis Laboratory) are available for the research team |
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| A. Galenic Laboratory
– analytical balances (Sartorius, Germany) – technical balances (Ohaus, SUA) – eccentric tablet press (Korsch, Germany) – drum hoop mixer (Erweka, Germany) – laboratory kneader (Erweka Germany) – laboratory wet granulator (Erweka, Germany) – laboratory fluid bed system for powder /granules drying, granulation (GEA-Aeromatic, Switzerland) – laboratory Wurster fluid bed – ultra-turax homogenizer (Ika, Germany) – DSC832e – Differential Scanning Calorimeter (Mettler Toledo, Switzerland) – TGA – Thermogravimetric Analyzer (Mettler Toledo, Switzerland) – climatic chambers for stability studies (Binder, Germany – climatic chambers with forced air convenction – VENTICELL 55 (BMT, Czechia) – vertical discs mill, vibrating balls mill – laser particle size analyzer (Fritsch, Germany)
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B. Drug Analysis Laboratory
– MicroNIR™ PAT-U Spectrometer (VIAVI, Italy) – FT-NIR spectrometer MPA (Bruker, Germany) – 2 dissolution testers (PharmaTest, Germany) – UV-Vis spectrophotometer (Jasco, Germany) – HPLC (Agilent, SUA) – disintegration tester (Erweka, Germany) – tablets hardness tester (Schleunige, Germany) – tablets friability tester (Erweka, Germany) – powder tappet/bulk density tester (Erweka) – powder flow tester (Copley Scientific, UK) – sieve analysis tester (Retsch, Germany) – pH-meter (Mettler Toledo, Switzerland) – centrifuge Sigma 2-16 (Sigma, Germany) – automate pipettes (Biohit, Finland) – ultrasonic bath – moisture analyzer (Ohaus, Germany) – titrator karl-fischer TitroLine® 7500 KF trace (SI Analytics, Germany) – optical microscope with video camera and software for image analysis (Optika, Italy) |
| Computers, software for data processing infrastructure
– DoE software: Modde 11.0 (Umetrics, Sweden), Unscrambler X (Camo, Norway); – multivariate data analysis and chemometric software: SIMCA-P 14.0 (Umetrics, Sweden), Unscrambler X (Camo, Norway), Opus Quant (Bruker, Germany); Details about the available research infrastructure are presented on ERRIS platform to the following address: https://erris.gov.ro/Laboratory-of-Pharmaceutical ”” |
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QbD-PAT MatrixRS 